A Type I Collagen-Targeted MR Imaging Probe for Staging Fibrosis in Crohn’s Disease

Fibrostenosis is a serious complication of Crohn’s disease (CD), affecting approximately one-half of all patients. Surgical resection is the typical clinical end due to ineffective antifibrotic therapy mainly through anti-inflammatory treatment and fibrosis can be reverted only at early stages. Move...

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Bibliographic Details
Main Authors: Zhoulei Li, Baolan Lu, Jinjiang Lin, Shaofu He, Li Huang, Yangdi Wang, Jixin Meng, Ziping Li, Shi-Ting Feng, Shaochun Lin, Ren Mao, Xue-Hua Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.762355/full