High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasma.

High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasma.

Circulating cell-free (ccf) fetal DNA comprises 3-20% of all the cell-free DNA present in maternal plasma. Numerous research and clinical studies have described the analysis of ccf DNA using next generation sequencing for the detection of fetal aneuploidies with high sensitivity and specificity. We...

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Bibliographic Details
Main Authors: Taylor J Jensen, Tricia Zwiefelhofer, Roger C Tim, Željko Džakula, Sung K Kim, Amin R Mazloom, Zhanyang Zhu, John Tynan, Tim Lu, Graham McLennan, Glenn E Palomaki, Jacob A Canick, Paul Oeth, Cosmin Deciu, Dirk van den Boom, Mathias Ehrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590217?pdf=render

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http://europepmc.org/articles/PMC3590217?pdf=render

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