Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury

Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury

We previously demonstrated that gene-modified umbilical cord blood mononuclear cells overexpressing a combination of recombinant neurotrophic factors are a promising therapeutic approach for cell-mediated gene therapy for neurodegenerative diseases, neurotrauma, and stroke. In this study, using a mi...

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Bibliographic Details
Main Authors: Rustem R Islamov, Farid V Bashirov, Mikhail E Sokolov, Andrei A Izmailov, Filip O Fadeev, Vage A Markosyan, Maria A Davleeva, Olga V Zubkova, Maxim M Smarov, Denis Yu Logunov, Boris S Naroditskyi, Ilnur I Salafutdinov, Albert A Rizvanov, Ramil G Turaev
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
chimeric ad5/35f virus; enhanced green fluorescent protein; gene-modified leucoconcentrate; mini pig; peripheral blood; personalized ex vivo gene therapy; plastic blood bag; spinal cord injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=2;spage=357;epage=361;aulast=Islamov

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=2;spage=357;epage=361;aulast=Islamov

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