Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via <i>p53</i> and JAK2-STAT3 Signaling

Ribosomes are the vital molecular machine for protein translation in a cell. Defects in several nucleolar proteins have been observed in human ribosomopathies. In zebrafish, a deficiency in these ribosomal proteins often results in an anemic phenotype. It remains to be determined whether any other r...

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Bibliographic Details
Main Authors: Fang Liang, Xiaochan Lu, Biyu Wu, Yexin Yang, Wei Qin
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/4/538