DNA methylation and mRNA expression of glutathione S-transferase alpha 4 are associated with intracranial aneurysms in a gender-dependent manner

DNA methylation and mRNA expression of glutathione S-transferase alpha 4 are associated with intracranial aneurysms in a gender-dependent manner

Objective: We performed a case-control study to investigate the correlation between DNA methylation and mRNA expression of the glutathione S-transferase alpha 4 (GSTA4) gene and the risk of intracranial aneurysm (IA) in the Chinese Han population.Methods: After propensity score matching, 44 pairs of...

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Bibliographic Details
Main Authors: Tianqi Xu, Xi Yu, Shenjun Zhou, Yiwen Wu, Xinpeng Deng, Yuefei Wu, Shiyi Wang, Xiang Gao, Sheng Nie, Chenhui Zhou, Jie Sun, Yi Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
intracranial aneurysm
DNA methylation
mRNA expression
5-aza-2'-deoxycytidine
glutathione S-tranferase alpha 4
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1079455/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1079455/full

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