Functional Characterization of Circulating Mumps Viruses with Stop Codon Mutations in the Small Hydrophobic Protein

Functional Characterization of Circulating Mumps Viruses with Stop Codon Mutations in the Small Hydrophobic Protein

ABSTRACT Between 2015 and 2017, routine molecular surveillance in the United States detected multiple mumps viruses (MuVs) with mutations in the small hydrophobic (SH) gene compared to a reference virus of the same genotype. These mutations include an unusual pattern of uracil-to-cytosine hypermutat...

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Bibliographic Details
Main Authors: Rita Czakó Stinnett, Andrew S. Beck, Elena N. Lopareva, Rebecca J. McNall, Donald R. Latner, Carole J. Hickman, Paul A. Rota, Bettina Bankamp
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mSphere
Subjects:
SH protein
genomics
molecular epidemiology
mumps virus
next-generation sequencing
paramyxovirus
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00840-20

Internet

https://journals.asm.org/doi/10.1128/mSphere.00840-20

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