IGF1R and MAPK15 Emerge as Potential Targets of Pentabromobenzylisothioureas in Lung Neuroendocrine Neoplasms

Pentabromobenzylisothioureas are antitumor agents with diverse properties, including the inhibition of MAPK15, IGF1R and PKD1 kinases. Their dysregulation has been implicated in the pathogenesis of several cancers, including bronchopulmonary neuroendocrine neoplasms (BP-NEN). The present study asses...

Celý popis

Podrobná bibliografie
Hlavní autoři: Ewelina Motylewska, Marcin Braun, Zygmunt Kazimierczuk, Hanna Ławnicka, Henryk Stępień
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2020-10-01
Edice:Pharmaceuticals
Témata:
On-line přístup:https://www.mdpi.com/1424-8247/13/11/354