Type A1 but Not Type A2 Botulinum Toxin Decreases the Grip Strength of the Contralateral Foreleg Through Axonal Transport From the Toxin-Treated Foreleg of Rats

Type A1 but Not Type A2 Botulinum Toxin Decreases the Grip Strength of the Contralateral Foreleg Through Axonal Transport From the Toxin-Treated Foreleg of Rats

Abstract.: The adverse effects of botulinum LL toxin and neurotoxin produced by subtype A1 (A1LL and A1NTX) are becoming issues, as the toxins could diffuse from the toxin-treated (ipsilateral) to contralateral muscles. We have attempted to produce neurotoxin from subtype A2 (A2NTX) with an amino ac...

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Main Authors: Yasushi Torii, Norio Akaike, Tetsuhiro Harakawa, Keiko Kato, Nakaba Sugimoto, Yoshitaka Goto, Shinji Nakahira, Tomoko Kohda, Shunji Kozaki, Ryuji Kaji, Akihiro Ginnaga
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306140

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http://www.sciencedirect.com/science/article/pii/S1347861319306140

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