Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

The immune response to Zika virus is required to curtail the infection and avoid immunopathology, but may be involved in the associated pathophysiology. Here the authors show that viral persistence and tissue tropism is shaped by an early innate immune response in a pigtail macaque model of infectio...

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Bibliographic Details
Main Authors: Megan A. O’Connor, Jennifer Tisoncik-Go, Thomas B. Lewis, Charlene J. Miller, Debra Bratt, Cassie R. Moats, Paul T. Edlefsen, Jeremy Smedley, Nichole R. Klatt, Michael Gale, Deborah Heydenburg Fuller
Format: Article
Language:English
Published: Nature Portfolio 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05826-w

Internet

https://doi.org/10.1038/s41467-018-05826-w

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