RNA-binding protein IGF2BP2 suppresses metastasis of clear cell renal cell carcinoma by enhancing CKB mRNA stability and expression

RNA-binding protein IGF2BP2 suppresses metastasis of clear cell renal cell carcinoma by enhancing CKB mRNA stability and expression

Clear cell renal cell carcinoma (ccRCC) is the most prevalent kidney cancer, with a highly aggressive phenotype and poor prognosis. RNA binding proteins (RBPs) play crucial roles in post-transcriptional gene regulation and have been implicated in tumorigenesis. RBPs have the potential to become a ne...

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Bibliographic Details
Main Authors: Junwu Ren, Bo Huang, Wei Li, Yongquan Wang, Xiaojuan Pan, Qiang Ma, Yuying Liu, Xiaolin Wang, Ce Liang, Yuying Zhang, Shimin Wang, Feifei Yang, Haiping Li, Hao Ning, Yan Jiang, Changhong Qin, Ai Ran, Bin Xiao
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Translational Oncology
Subjects:
Clear cell renal cell carcinoma
IGF2BP2
CKB
mRNA stability
RNA binding protein
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000299

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http://www.sciencedirect.com/science/article/pii/S1936523324000299

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