Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system

Hepatitis C virus (HCV) remains a global public health challenge with an estimated 71 million people chronically infected, with surges in new cases and no effective vaccine. New methods are needed to study the human immune response to HCV since in vivo animal models are limited and in vitro cancer c...

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Bibliographic Details
Main Authors: Vaishaali Natarajan, Camille R. Simoneau, Ann L. Erickson, Nathan L. Meyers, Jody L. Baron, Stewart Cooper, Todd C. McDevitt, Melanie Ott
Format: Article
Language:English
Published: The Royal Society 2022-03-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210320