Towards standardization of the parameters for opening the blood–brain barrier with focused ultrasound to treat glioblastoma multiforme: A systematic review of the devices, animal models, and therapeutic compounds used in rodent tumor models

Towards standardization of the parameters for opening the blood–brain barrier with focused ultrasound to treat glioblastoma multiforme: A systematic review of the devices, animal models, and therapeutic compounds used in rodent tumor models

Glioblastoma multiforme (GBM) is a deadly and aggressive malignant brain cancer that is highly resistant to treatments. A particular challenge of treatment is caused by the blood–brain barrier (BBB), the relatively impermeable vasculature of the brain. The BBB prevents large molecules from entering...

Full description

Bibliographic Details
Main Authors: Rasika Thombre, Griffin Mess, Kelley M. Kempski Leadingham, Shivani Kapoor, Andrew Hersh, Molly Acord, Tarana Kaovasia, Nicholas Theodore, Betty Tyler, Amir Manbachi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
blood-brain barrier
chemotherapy
focused ultrasound
glioblastoma multiforme
immunotherapy
microbubble
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1072780/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1072780/full

Similar Items