Induction of the Erythroid Differentiation of K562 Cells Is Coupled with Changes in the Inter-Chromosomal Contacts of rDNA Clusters

Induction of the Erythroid Differentiation of K562 Cells Is Coupled with Changes in the Inter-Chromosomal Contacts of rDNA Clusters

The expression of clusters of rDNA genes influences pluripotency; however, the underlying mechanisms are not yet known. These clusters shape inter-chromosomal contacts with numerous genes controlling differentiation in human and <i>Drosophila</i> cells. This suggests a possible role of t...

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Bibliographic Details
Main Authors: Nickolai A. Tchurikov, Elena S. Klushevskaya, Ildar R. Alembekov, Antonina N. Kretova, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
rDNA clusters
differentiation
inter-chromosomal contacts
4C
gene expression
K562
Online Access:https://www.mdpi.com/1422-0067/24/12/9842

Internet

https://www.mdpi.com/1422-0067/24/12/9842

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