MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming

Summary: Cell reprogramming is thought to be associated with a full metabolic switch from an oxidative- to a glycolytic-based metabolism. However, neither the dynamics nor the factors controlling this metabolic switch are fully understood. By using cellular, biochemical, protein array, metabolomic,...

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Main Authors: Javier Prieto, Arnold Y. Seo, Marian León, Fulvio Santacatterina, Laura Torresano, Martina Palomino-Schätzlein, Karen Giménez, Azahara Vallet-Sánchez, Xavier Ponsoda, Antonio Pineda-Lucena, José M. Cuezva, Jennifer Lippincott-Schwartz, Josema Torres
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118304417