Combined Subthalamic and Nigral Stimulation Modulates Temporal Gait Coordination and Cortical Gait-Network Activity in Parkinson’s Disease

BackgroundFreezing of gait (FoG) is a disabling burden for Parkinson’s disease (PD) patients with poor response to conventional therapies. Combined deep brain stimulation of the subthalamic nucleus and substantia nigra (STN+SN DBS) moved into focus as a potential therapeutic option to treat the park...

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Detalhes bibliográficos
Main Authors: Jonas R. Wagner, Miriam Schaper, Wolfgang Hamel, Manfred Westphal, Christian Gerloff, Andreas K. Engel, Christian K. E. Moll, Alessandro Gulberti, Monika Pötter-Nerger
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2022-02-01
Colecção:Frontiers in Human Neuroscience
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnhum.2022.812954/full