PTEN Mediates the Silencing of Unintegrated HIV-1 DNA

The integration of viral DNA into a host genome is an important step in HIV-1 replication. However, due to the high failure rate of integration, the majority of viral DNA exists in an unintegrated state during HIV-1 infection. In contrast to the robust expression from integrated viral DNA, unintegra...

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Bibliographic Details
Main Authors: An Thanh Phan, Yiping Zhu
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/16/2/291