PTEN Mediates the Silencing of Unintegrated HIV-1 DNA
The integration of viral DNA into a host genome is an important step in HIV-1 replication. However, due to the high failure rate of integration, the majority of viral DNA exists in an unintegrated state during HIV-1 infection. In contrast to the robust expression from integrated viral DNA, unintegra...
Main Authors: | An Thanh Phan, Yiping Zhu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-02-01
|
Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/16/2/291 |
Similar Items
-
Silencing of Unintegrated Retroviral DNAs
by: Stephen P. Goff
Published: (2021-11-01) -
Two lymphoid cell lines potently silence unintegrated HIV-1 DNAs
by: Franziska K. Geis, et al.
Published: (2022-07-01) -
Human immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA
by: Emeagwali Nkiruka, et al.
Published: (2012-11-01) -
A comparative analysis of unintegrated HIV-1 DNA measurement as a potential biomarker of the cellular reservoir in the blood of patients controlling and non-controlling viral replication
by: Chiara Orlandi, et al.
Published: (2020-05-01) -
Different Pathways Conferring Integrase Strand-Transfer Inhibitors Resistance
by: Clémence Richetta, et al.
Published: (2022-11-01)