Protocol for generating lung and liver metastasis in mice using models that bypass intravasation

Summary: Forced metastasis models, those in which the step of intravasation is bypassed, can be used to investigate the mechanisms underlying metastasis and evaluate potential therapeutic targets. Here, we present a protocol for using three forced models of lung and liver metastasis to generate meta...

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Bibliographic Details
Main Authors: Jöran Lücke, Tao Zhang, Dimitra E. Zazara, Philipp Seeger, Jacob R. Izbicki, Thilo Hackert, Samuel Huber, Anastasios D. Giannou
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723006639