Tolerogenic dendritic cells and negative vaccination in transplantation: from rodents to clinical trials

Tolerogenic dendritic cells and negative vaccination in transplantation: from rodents to clinical trials

The use of immunosuppressive drugs to treat transplant recipients has markedly reduced the incidence of acute rejection and early graft loss. However, such treatments have numerous adverse side effects and fail to prevent chronic allograft dysfunction. In this context, therapies based on the adoptiv...

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Bibliographic Details
Main Authors: Aurelie eMoreau, Emilie eVarey, Gaelle eBeriou, Marcelo eHill, Laurence eDelbos, Mercedes eSegovia, Maria-Cristina eCuturi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
Immune Tolerance
Transplantation
Clinical Trial
Translational research
Tolerogenic dendritic cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00218/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00218/full

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