RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense.

RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense.

RpkA (Receptor phosphatidylinositol kinase A) is an unusual seven-helix transmembrane protein of Dictyostelium discoideum with a G protein coupled receptor (GPCR) signature and a C-terminal lipid kinase domain (GPCR-PIPK) predicted as a phosphatidylinositol-4-phosphate 5-kinase. RpkA-homologs are pr...

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Bibliographic Details
Main Authors: Tanja Y Riyahi, Frederike Frese, Michael Steinert, Napoleon N Omosigho, Gernot Glöckner, Ludwig Eichinger, Benoit Orabi, Robin S B Williams, Angelika A Noegel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206951?pdf=render

Internet

http://europepmc.org/articles/PMC3206951?pdf=render

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