Surgery compared to fibrinolytic therapy for symptomatic left-sided prosthetic heart valve thrombosis (SAFE-PVT): Rationale and design of a randomized controlled trial

Background: Left-sided mechanical prosthetic heart valve thrombosis (PVT) occurs because of suboptimal anticoagulation and is common in low-resource settings. Urgent surgery and fibrinolytic therapy (FT) are the two treatment options available for this condition. Urgent surgery is a high-risk proced...

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Main Authors: Niveditha Devasenapathy, Velayoudam Devagourou, Milind P. Hote, Palleti Rajashekar, Bharathraj Kidambi, Aayush Singal, Mohsin Raj Mantoo, Manoj Soni, Gaurav Purohit, Sandeep Singh, Ganesan Karthikeyan
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Indian Heart Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S0019483224000865