Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins
The ancient paralogs premelanosome protein (<i>PMEL</i>) and glycoprotein nonmetastatic melanoma protein B (<i>GPNMB</i>) have independently emerged as intriguing disease loci in recent years. Both proteins possess common functional domains and variants that cause a shared sp...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/12/3529 |