Goals and Challenges of Stem Cell-Based Therapy for Corneal Blindness Due to Limbal Deficiency

Goals and Challenges of Stem Cell-Based Therapy for Corneal Blindness Due to Limbal Deficiency

Corneal failure is a highly prevalent cause of blindness. One special cause of corneal failure occurs due to malfunction or destruction of the limbal stem cell niche, upon which the superficial cornea depends for homeostatic maintenance and wound healing. Failure of the limbal niche is referred to a...

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Bibliographic Details
Main Authors: Margarita Calonge, Teresa Nieto-Miguel, Ana de la Mata, Sara Galindo, José M. Herreras, Marina López-Paniagua
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
blindness
cell therapy
CLET
cornea
limbal niche
limbal stem cell
Online Access:https://www.mdpi.com/1999-4923/13/9/1483

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https://www.mdpi.com/1999-4923/13/9/1483

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