Synthesis of Lysine Methyltransferase Inhibitors

Lysine methyltransferase which catalyze methylation of histone and nonhistone proteins, play a crucial role in diverse biological processes and has emerged as a promising target for the development of various human diseases, including cancer, inflammation, and psychiatric disorders. However, inhibit...

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Bibliographic Details
Main Authors: Tao eYe, Chunngai eHui
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00044/full