Mesoporous silica microparticles gated with a bulky azo derivative for the controlled release of dyes/drugs in colon

Mesoporous silica microparticles gated with a bulky azo derivative for the controlled release of dyes/drugs in colon

Mesoporous silica microparticles were prepared, loaded with the dye safranin O (M-Saf) or with the drug budesonide (M-Bud) and capped by the grafting of a bulky azo derivative. Cargo release from M-Saf at different pH values (mimicking those found in the gastrointestinal tract) in the absence or pre...

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Bibliographic Details
Main Authors: Daniel Ferri, Pablo Gaviña, Margarita Parra, Ana M. Costero, Jamal El Haskouri, Pedro Amorós, Virginia Merino, Adrián H. Teruel, Félix Sancenón, Ramón Martínez-Máñez
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
mesoporous silica microparticles
gated materials
controlled drug release
colon targeting
inflammatory bowel disease
budesonide
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180873

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180873

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