Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model
Abstract Background Members of the HMGN protein family modulate chromatin structure and influence epigenetic modifications. HMGN1 and HMGN2 are highly expressed during early development and in the neural stem/progenitor cells of the developing and adult brain. Here, we investigate whether HMGN prote...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
|
Series: | Epigenetics & Chromatin |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13072-019-0320-7 |