Promotion of homology-directed DNA repair by polyamines
The maintenance polyamines homeostasis is important for cell growth, and several cancers harbor elevated levels of polyamines that may contribute to sustained proliferative potential. Here the authors demonstrate that polyamines participate in DNA double-strand break repair through the stimulation o...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-08011-1 |