A Bioassay-Guided Fractionation of Rosemary Leaf Extract Identifies Carnosol as a Major Hypertrophy Inducer in Human Skeletal Muscle Cells

A Bioassay-Guided Fractionation of Rosemary Leaf Extract Identifies Carnosol as a Major Hypertrophy Inducer in Human Skeletal Muscle Cells

A good quality of life requires maintaining adequate skeletal muscle mass and strength, but therapeutic agents are lacking for this. We developed a bioassay-guided fractionation approach to identify molecules with hypertrophy-promoting effect in human skeletal muscle cells. We found that extracts fr...

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Bibliographic Details
Main Authors: Sylvie Morel, Gérald Hugon, Manon Vitou, Marie Védère, Françoise Fons, Sylvie Rapior, Nathalie Saint, Gilles Carnac
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nutrients
Subjects:
<i>Salvia rosmarinus</i>
stem cells
diterpene
proteasome
muscle mass
Online Access:https://www.mdpi.com/2072-6643/13/12/4190

Internet

https://www.mdpi.com/2072-6643/13/12/4190

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