Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis

Abstract Background The family with sequence similarity 20-member C (FAM20C) kinase, a Golgi casein kinase, which is responsible for phosphorylating the majority of the extracellular phosphoproteins within S-x-E/pS motifs, and is fundamentally associated with multiple biological processes to maintai...

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Bibliographic Details
Main Authors: Xinpeng Liu, Lili Jiang, Wenxuan Zhang, Jiahui Zhang, Xinrui Luan, Yuanbo Zhan, Tuo Wang, Junlong Da, Lixue Liu, Shujian Zhang, Yuyao Guo, Kai Zhang, Zhiping Wang, Nan Miao, Xiaohua Xie, Peihong Liu, Ying Li, Han jin, Bin Zhang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-023-04275-4