RNA inverse folding using Monte Carlo tree search

RNA inverse folding using Monte Carlo tree search

Abstract Background Artificially synthesized RNA molecules provide important ways for creating a variety of novel functional molecules. State-of-the-art RNA inverse folding algorithms can design simple and short RNA sequences of specific GC content, that fold into the target RNA structure. However,...

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Bibliographic Details
Main Authors: Xiufeng Yang, Kazuki Yoshizoe, Akito Taneda, Koji Tsuda
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Monte Carlo tree search
RNA inverse folding
Local update
Pseudoknotted structure
Online Access:http://link.springer.com/article/10.1186/s12859-017-1882-7

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http://link.springer.com/article/10.1186/s12859-017-1882-7

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