Interleukin-22 in the pathogenesis and potential treatment of liver diseases

Interleukin (IL)-22, a member of the IL-10 cytokine family, plays critical roles in tissue repair and host defense. IL-22 binds to its hetereodimeric receptor (R) composed of IL-22R1 and IL-10R2 and activates downstream signaling, including Signal transducer and activator of transcription 3 (STAT3)...

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Bibliographic Details
Main Authors: Shi Yin, Dechun Feng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2017-09-01
Series:Liver Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2542568417000460