Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

Summary: Functional and phenotypic heterogeneity of dendritic cells (DCs) play crucial roles in facilitating the development of diverse immune responses essential for host protection. Here, we report that KDM5C, a histone lysine demethylase, regulates conventional or classical DC (cDC) and plasmacyt...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Hannah Guak, Matthew Weiland, Alexandra Vander Ark, Lukai Zhai, Kin Lau, Mario Corrado, Paula Davidson, Ebenezer Asiedu, Batsirai Mabvakure, Shelby Compton, Lisa DeCamp, Catherine A. Scullion, Russell G. Jones, Sara M. Nowinski, Connie M. Krawczyk
Format: Artykuł
Język:English
Wydane: Elsevier 2024-08-01
Seria:Cell Reports
Hasła przedmiotowe:
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2211124724008350