PAK1 protein expression in the auditory cortex of schizophrenia subjects.

Deficits in auditory processing are among the best documented endophenotypes in schizophrenia, possibly due to loss of excitatory synaptic connections. Dendritic spines, the principal post-synaptic target of excitatory projections, are reduced in schizophrenia. p21-activated kinase 1 (PAK1) regulate...

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Bibliographic Details
Main Authors: Anthony J Deo, Isaac M Goldszer, Siyu Li, James V DiBitetto, Ruth Henteleff, Allan Sampson, David A Lewis, Peter Penzes, Robert A Sweet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3632562?pdf=render