In Vitro Inhibition of Replication of Dengue Virus Serotypes 1–4 by siRNAs Bound to Non-Toxic Liposomes

Dengue virus is a ssRNA+ flavivirus, which produces the dengue disease in humans. Currently, no specific treatment exists. siRNAs regulate gene expression and have been used systematically to silence viral genomes; however, they require controlled release. Liposomes show favorable results encapsulat...

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Bibliographic Details
Main Authors: Carlos Andrés Rodriguez-Salazar, Delia Piedad Recalde-Reyes, Juan Pablo Bedoya, Leonardo Padilla-Sanabria, Jhon Carlos Castaño-Osorio, Maria Isabel Giraldo
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/2/339