Embryonic morphogen nodal promotes breast cancer growth and progression.

Breast cancers expressing human embryonic stem cell (hESC)-associated genes are more likely to progress than well-differentiated cancers and are thus associated with poor patient prognosis. Elevated proliferation and evasion of growth control are similarly associated with disease progression, and ar...

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Bibliographic Details
Main Authors: Daniela F Quail, Guihua Zhang, Logan A Walsh, Gabrielle M Siegers, Dylan Z Dieters-Castator, Scott D Findlay, Heather Broughton, David M Putman, David A Hess, Lynne-Marie Postovit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492336?pdf=render