Common genetic variants contribute to heritability of age at onset of schizophrenia

Abstract Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease. We explored the genetic architecture of AAO with a genome-wide association study (GWAS), heritability, poly...

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Bibliographic Details
Main Authors: Ester Sada-Fuente, Selena Aranda, Sergi Papiol, Urs Heilbronner, María Dolores Moltó, Eduardo J. Aguilar, Javier González-Peñas, Álvaro Andreu-Bernabeu, Celso Arango, Benedicto Crespo-Facorro, Ana González-Pinto, Lourdes Fañanás, Barbara Arias, Julio Bobes, Javier Costas, Lourdes Martorell, Thomas G. Schulze, Janos L. Kalman, Elisabet Vilella, Gerard Muntané
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02508-0