Rapamycin is highly effective in murine models of immune-mediated bone marrow failure

Acquired aplastic anemia, the prototypical bone marrow failure disease, is characterized by pancytopenia and marrow hypoplasia. Most aplastic anemia patients respond to immunosuppressive therapy, usually with anti-thymocyte globulin and cyclosporine, but some relapse on cyclosporine withdrawal or re...

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Bibliographic Details
Main Authors: Xingmin Feng, Zenghua Lin, Wanling Sun, Maile K. Hollinger, Marie J. Desierto, Keyvan Keyvanfar, Daniela Malide, Pawel Muranski, Jichun Chen, Neal S. Young
Format: Article
Language:English
Published: Ferrata Storti Foundation 2017-10-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/8217