Chromosomal imbalances detected in primary bone tumors by comparative genomic hybridization and interphase fluorescence in situ hybridization

Chromosomal imbalances detected in primary bone tumors by comparative genomic hybridization and interphase fluorescence in situ hybridization

We applied a combination of comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH), to characterize the genetic aberrations in three osteosarcomas (OS) and one Ewing's sarcoma. CGH identified recurrent chromosomal losses at 10p14-pter and gains at 8q22.3-24.1 in O...

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Bibliographic Details
Main Authors: Marcelo Razera Baruffi, Edgard Edward Engel, Jeremy Andrew Squire, Luis Gonzaga Tone, Silvia Regina Rogatto
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2003-01-01
Series:Genetics and Molecular Biology
Subjects:
comparative genomic hybridization
CGH
osteosarcoma
Ewing's Sarcoma
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000200001

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000200001

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