Biophysical models applied to dementia patients reveal links between geographical origin, gender, disease duration, and loss of neural inhibition

Biophysical models applied to dementia patients reveal links between geographical origin, gender, disease duration, and loss of neural inhibition

Abstract Background The hypothesis of decreased neural inhibition in dementia has been sparsely studied in functional magnetic resonance imaging (fMRI) data across patients with different dementia subtypes, and the role of social and demographic heterogeneities on this hypothesis remains to be addre...

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Bibliographic Details
Main Authors: Sebastian Moguilner, Rubén Herzog, Yonatan Sanz Perl, Vicente Medel, Josefina Cruzat, Carlos Coronel, Morten Kringelbach, Gustavo Deco, Agustín Ibáñez, Enzo Tagliazucchi
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Dementia
Neurodegeneration
Biophysical modeling
Hyperexcitability
Variability
Gender
Online Access:https://doi.org/10.1186/s13195-024-01449-0

Internet

https://doi.org/10.1186/s13195-024-01449-0

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