A method for 3D immunostaining and optical imaging of the mouse brain demonstrated in neural progenitor cells.

It is important to understand changes in cell distribution that occur as a part of disease progression. This is typically achieved using standard sectioning and immunostaining, however, many structures and cell distribution patterns are not readily appreciated in two-dimensions, including the distri...

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Bibliographic Details
Main Authors: Jacqueline A Gleave, Jason P Lerch, R Mark Henkelman, Brian J Nieman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3735582?pdf=render