Immunohistochemical expression of programmed death-ligand 1 and CD8 in glioblastomas

Immunohistochemical expression of programmed death-ligand 1 and CD8 in glioblastomas

Background Glioblastoma is the most aggressive primary malignant brain tumor in adults and is characterized by poor prognosis. Immune evasion occurs via programmed death-ligand 1 (PD-L1)/programmed death receptor 1 (PD-1) interaction. Some malignant tumors have responded to PD-L1/PD-1 blockade treat...

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Bibliographic Details
Main Authors: Dina Mohamed El Samman, Manal Mohamed El Mahdy, Hala Sobhy Cousha, Zeinab Abd El Rahman Kamar, Khaled Abdel Karim Mohamed, Hoda Hassan Abou Gabal
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2021-11-01
Series:Journal of Pathology and Translational Medicine
Subjects:
glioblastoma
programmed death ligand 1
tumor-infiltrating lymphocytes
cd8
survival analysis
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2021-08-04.pdf

Internet

http://www.jpatholtm.org/upload/pdf/jptm-2021-08-04.pdf

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