Study of Protein Phosphatase 2A (PP2A) Activity in LPS-Induced Tolerance Using Fluorescence-Based and Immunoprecipitation-Aided Methodology

Study of Protein Phosphatase 2A (PP2A) Activity in LPS-Induced Tolerance Using Fluorescence-Based and Immunoprecipitation-Aided Methodology

Protein phosphatase 2A (PP2A) is one of the most abundant intracellular serine/threonine (Ser/Thr) phosphatases accounting for 1% of the total cellular protein content. PP2A is comprised of a heterodimeric core enzyme and a substrate-specific regulatory subunit. Potentially, at least seventy differe...

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Bibliographic Details
Main Authors: Lei Sun, Adlai L. Pappy II, Tiffany T. Pham, Thomas P. Shanley
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Biomolecules
Subjects:
PP2A
immune tolerance
phosphatase assay
Online Access:http://www.mdpi.com/2218-273X/5/3/1284

Internet

http://www.mdpi.com/2218-273X/5/3/1284

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