Predicting response to immunotherapy in gastric cancer via assessing perineural invasion-mediated inflammation in tumor microenvironment

Predicting response to immunotherapy in gastric cancer via assessing perineural invasion-mediated inflammation in tumor microenvironment

Abstract Background The perineural invasion (PNI)-mediated inflammation of the tumor microenvironment (TME) varies among gastric cancer (GC) patients and exhibits a close relationship with prognosis and immunotherapy. Assessing the neuroinflammation of TME is important in predicting the response to...

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Bibliographic Details
Main Authors: Xunjun Li, Yiyun Wang, ZhongYa Zhai, Qingyi Mao, Dianjie Chen, Luxi Xiao, Shuai Xu, Qilin Wu, Keming Chen, Qiantong Hou, Qinglie He, Yuyang Shen, Manchun Yang, Zishan Peng, Siqing He, Xuanhui Zhou, Haoyang Tan, Shengwei Luo, Chuanfa Fang, Guoxin Li, Tao Chen
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Perinueral invasion(PNI)
Gastric cancer(GC)
Inflammatory
Tumor microenvironment(TME)
Neuroinflammation infiltration(NII) score system
Online Access:https://doi.org/10.1186/s13046-023-02730-0

Internet

https://doi.org/10.1186/s13046-023-02730-0

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