PDE4-Mediated cAMP Signalling

cAMP is the archetypal and ubiquitous second messenger utilised for the fine control of many cardiovascular cell signalling systems. The ability of cAMP to elicit cell surface receptor-specific responses relies on its compartmentalisation by cAMP hydrolysing enzymes known as phosphodiesterases. One...

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Bibliographic Details
Main Authors: Bracy A. Fertig, George S. Baillie
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:http://www.mdpi.com/2308-3425/5/1/8