Organic Cation Transporters (OCTs) in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium

Organic Cation Transporters (OCTs) in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium

Organic cation transporters (OCTs) and novel organic cation transporters (OCTNs) are responsible for drug delivery in the intestine and kidney; in the lung, OCTs mediate inhaled drugs’ transport, although their physiological role in airways remains poorly understood. The studies addressing OCTs/OCTN...

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Bibliographic Details
Main Authors: Amelia Barilli, Rossana Visigalli, Francesca Ferrari, Maria Di Lascia, Benedetta Riccardi, Paola Puccini, Valeria Dall’Asta, Bianca Maria Rotoli
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomedicines
Subjects:
bronchial epithelium
organic cation transporters
pulmonary drug delivery
<i>SLC22A1</i> (OCT1)
<i>SLC22A3</i> (OCT3)
<i>SLC6A14</i> (ATB<sup>0,+</sup>)
Online Access:https://www.mdpi.com/2227-9059/8/5/127

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https://www.mdpi.com/2227-9059/8/5/127

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