Impaired host resistance to Salmonella during helminth co-infection is restored by anthelmintic treatment prior to bacterial challenge.

Impaired host resistance to Salmonella during helminth co-infection is restored by anthelmintic treatment prior to bacterial challenge.

Intestinal helminth infection can impair host resistance to co-infection with enteric bacterial pathogens. However, it is not known whether helminth drug-clearance can restore host resistance to bacterial infection. Using a mouse helminth-Salmonella co-infection system, we show that anthelmintic tre...

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Bibliographic Details
Main Authors: Tara P Brosschot, Katherine M Lawrence, Brandon E Moeller, Mia H E Kennedy, Rachael D FitzPatrick, Courtney M Gauthier, Dongju Shin, Dominique M Gatti, Kate M E Conway, Lisa A Reynolds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009052

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https://doi.org/10.1371/journal.pntd.0009052

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