NOD1 deficiency ameliorates the progression of diabetic retinopathy by modulating bone marrow–retina crosstalk

NOD1 deficiency ameliorates the progression of diabetic retinopathy by modulating bone marrow–retina crosstalk

Abstract Background Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) plays a pivotal role in inducing metabolic inflammation in diabetes. Additionally, the NOD1 ligand disrupts the equilibrium of bone marrow-derived hematopoietic stem/progenitor cells, a process that has immense...

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Bibliographic Details
Main Authors: Jingwen Qiu, Jing Wu, Wenwen Chen, Yu Ruan, Jingning Mao, Shue Li, Xuan Tang, Lei Zhao, Shengbing Li, Ke Li, Dongfang Liu, Yaqian Duan
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Stem Cell Research & Therapy
Subjects:
Nucleotide-binding oligomerization domain-containing protein 1
Diabetic retinopathy
Hematopoietic stem/progenitor cells
Macrophage
Inflammation
Online Access:https://doi.org/10.1186/s13287-024-03654-y

Internet

https://doi.org/10.1186/s13287-024-03654-y

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