Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast

Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast

Ageing-related processes are largely conserved, with simple organisms remaining the main platform to discover and dissect new ageing-associated genes. Yeasts provide potent model systems to study cellular ageing owing their amenability to systematic functional assays under controlled conditions. Eve...

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Bibliographic Details
Main Authors: Catalina A. Romila, StJohn Townsend, Michal Malecki, Stephan Kamrad, María Rodríguez-López, Olivia Hillson, Cristina Cotobal, Markus Ralser, Jürg Bähler
Format: Article
Language:English
Published: Shared Science Publishers OG 2021-05-01
Series:Microbial Cell
Subjects:
cellular ageing
longevity
parallel genetic screen
competitive growth
lifespan mutants
bar-seq
s. pombe
Online Access:http://microbialcell.com/researcharticles/2021a-romila-microbial-cell/

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http://microbialcell.com/researcharticles/2021a-romila-microbial-cell/

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