Modeling Neurovascular Disorders and Therapeutic Outcomes with Human-Induced Pluripotent Stem Cells

The neurovascular unit (NVU) is composed of neurons, astrocytes, pericytes, and endothelial cells that form the blood–brain barrier (BBB). The NVU regulates material exchange between the bloodstream and the brain parenchyma, and its dysfunction is a primary or secondary cause of many cerebrovascular...

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Bibliographic Details
Main Authors: Allison M. Bosworth, Shannon L. Faley, Leon M. Bellan, Ethan S. Lippmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fbioe.2017.00087/full