Single-cell transcriptomics reveals functionally specialized vascular endothelium in brain

The blood-brain barrier (BBB) limits the entry of leukocytes and potentially harmful substances from the circulation into the central nervous system (CNS). While BBB defects are a hallmark of many neurological disorders, the cellular heterogeneity at the neurovascular interface, and the mechanisms g...

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Bibliographic Details
Main Authors: Hyun-Woo Jeong, Rodrigo Diéguez-Hurtado, Hendrik Arf, Jian Song, Hongryeol Park, Kai Kruse, Lydia Sorokin, Ralf H Adams
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/57520